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Symbol Name ID |
Ifnb1
interferon beta 1, fibroblast MGI:107657 |
| Darker colors indicate more annotations |
| Human Phenotypes | Leukemia |
| Disease(s) Associated with IFNB1 | |
| retinoblastoma |
| Mouse Phenotypes | increased T cell proliferation |
decreased pro-B cell number |
decreased neutrophil cell number |
decreased mature B cell number |
decreased macrophage cell number |
decreased monocyte cell number |
abnormal osteoclast morphology |
abnormal spleen primary B follicle morphology |
decreased IgG level |
abnormal macrophage physiology |
abnormal microglial cell physiology |
decreased circulating interferon-alpha level |
decreased circulating interferon-beta level |
abnormal complement protein level |
impaired complement alternative pathway |
increased interferon-gamma secretion |
decreased interleukin-1 beta secretion |
increased interleukin-4 secretion |
decreased tumor necrosis factor secretion |
increased tumor necrosis factor secretion |
decreased susceptibility to induced arthritis |
increased susceptibility to experimental autoimmune encephalomyelitis |
CNS inflammation |
abnormal response to infection |
decreased susceptibility to bacterial infection |
increased susceptibility to Poxviridae infection |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||
| Ifnb1tm1Acgp/Ifnb1tm1Acgp | |||||||||||||||||||||||||||
| Ifnb1tm1Tl/Ifnb1tm1Tl | |||||||||||||||||||||||||||
| Ifnb1tm1Ttg/Ifnb1tm1Ttg | |||||||||||||||||||||||||||
| Tg(CAG-C1qtnf6)#Yiw/0 | |||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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